Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology) Book PDF, ePub eBook

Join our eBook service for unlimited books & audiobooks. Get a free 7 day subscription! ↓↓↓↓↓


Book Descriptions:
Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area.
The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease.
Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets.
We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology)

From reader reviews:

Donald Hidalgo:

In this 21st century, people become competitive in each and every way. By being competitive today, people have do something to make them survives, being in the middle of the crowded place and notice by surrounding. One thing that sometimes many people have underestimated the idea for a while is reading. Sure, by reading a e-book your ability to survive raise then having chance to remain than other is high. For yourself who want to start reading a book, we give you this particular Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology) book as basic and daily reading e-book. Why, because this book is more than just a book.

Antoinette Lefebre:

Spent a free time for you to be fun activity to do! A lot of people spent their free time with their family, or their friends. Usually they doing activity like watching television, likely to beach, or picnic within the park. They actually doing ditto every week. Do you feel it? Will you something different to fill your own free time/ holiday? May be reading a book is usually option to fill your free time/ holiday. The first thing that you will ask may be what kinds of publication that you should read. If you want to try out look for book, may be the e-book untitled Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology) can be great book to read. May be it could be best activity to you.

Connie Nixon:

Do you really one of the book lovers? If so, do you ever feeling doubt when you are in the book store? Attempt to pick one book that you just dont know the inside because don't evaluate book by its protect may doesn't work the following is difficult job because you are scared that the inside maybe not as fantastic as in the outside look likes. Maybe you answer may be Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology) why because the fantastic cover that make you consider in regards to the content will not disappoint an individual. The inside or content is usually fantastic as the outside or cover. Your reading 6th sense will directly direct you to pick up this book.

Keith Mayo:

As we know that book is very important thing to add our understanding for everything. By a guide we can know everything we want. A book is a list of written, printed, illustrated or even blank sheet. Every year ended up being exactly added. This book Membrane Receptors, Channels and Transporters in Pulmonary Circulation: 661 (Advances in Experimental Medicine and Biology) was filled about science. Spend your spare time to add your knowledge about your scientific research competence. Some people has several feel when they reading any book. If you know how big advantage of a book, you can really feel enjoy to read a publication. In the modern era like right now, many ways to get book that you wanted.